Journalists are in a unique position to bring transparency to a field of medicine that desperately needs it.
Until the public is informed that the recommendations made by the FDA for the treatment of menopause and andropause are not based in scientific fact, most people will be denied the opportunity to treat hypogonadism and its advanced form, profound hypogonadism. Hypogonadism is a devastating illness that is easily, safely, and effectively treated when recognized for its multiple hormone deficiencies. It is equally important not to use the regimens used in failed clinical trials because they in no way represent healthy hormone replacement, which is why they fail.
The following basic fact helps everyone understand what has happened when a hormone trial has failed:
A hormone trial only fails if it does not use hormone replacement in the normal range.
All hormone replacement trials are successful as long as they are designed to succeed. If a hormone replacement trial has failed it is because it was designed to fail.
This is all it takes to make a hormone replacement trial successful
- Measure hormone levels after replacement
- Adjust dosage to maintain normal hormone levels
That’s it. Let’s apply this logic to menopause clinical trials
- Are hormone levels measured – NO
- Is dosage adjusted – NO
Without these two steps a hormone trial will predictably fail. The further from normal hormone levels, the higher the incidence of side effects.
Let’s apply this logic to andropause clinical trials
- Are hormone levels measured – YES and NO
- Testosterone is measured but not progesterone, DHEA or estradiol
- Is dosage adjusted – YES and NO
- Testosterone is adjusted but not progesterone, DHEA or estradiol
Men’s trials are closer to success. Measuring and adjusting the other sex hormones would ensure success.
Since 1930 it is the norm to not measure any hormone levels in menopause clinical trials. Since there are no measurements no adjustments are made which ensures failure. Men’s hormone trials have evolved further than women’s. It is the norm to measure 1 hormone level however, leaving out the other 3 sex hormones that need measuring and adjusting as well.
As an investigative journalist dig into this. See that all recommendations for menopause are based on falsehoods. Ask yourselves, why not measure hormone levels? What would those levels reveal about the drug that was being used? Why not measure all of the hormone levels that are relevant to each other?
These are important questions that an investigative journalist can explore. Interview pharmacists and find out the drug studies on PremarinTM demonstrate that it provides no replacement. PremarinTM, the drug used over and over again in clinical trials creates abnormally hormone levels and is the drug all FDA recommendations are based on. Ask why recommendations are based on a drug that creates abnormal hormone levels. Wouldn’t it make more sense to base recommendations for menopause treatment on drugs that created normal hormone levels? Ask why hormones bio-identical to a horse are used when bio-identical hormones to human are available and much less expensive.
Interview someone from the Office of Human Research Protection (OHRP). Ask why hormone replacement trials for women do not measure hormone levels. Without proof, how can the drug used be allowed to be called hormone replacement? Why not announce publically that the drug used for decades in women’s hormone trials was referred to as HRT until 2007 then was quietly changed to HT, dropping the ‘R’ for replacement?
As for men’s hormone trials, ask the OHRP why only testosterone is being measured and the other relevant hormones aren’t measured. Replacing testosterone only without progesterone guarantees that the clinical trial won’t succeed. Replacing testosterone alone will predictably raise estradiol levels above normal. Progesterone in normal levels is needed to reduce estradiol levels to normal to protect the prostate from excess stimulation. This is basic human physiology. Where is the protection for men so their hormone trials can be successful?
An investigative journalist will be able to share with the public that all recommendations for menopause treatment are based on clinical trials designed to fail.
An investigative journalist will able be able to share with the public that all recommendations for the treatment of andropause are based on clinical trials designed to not fully succeed.
Once the public and the medical community sees that menopause and andropause are simply hormone deficiency illnesses that can be easily and effectively treated women and men will have the opportunity to vastly improve their health and quality of life. With effective treatment major diseases associated with hypogonadism would no longer be a theat. Osteoporosis could be eradicated in older women and men, prostate cancer would likely be significantly reduced as would breast cancer. Very importantly, sexual response and function would be a lifetime opportunity.
As an investigative journalist you can make a difference,
Use this list serve to work with other journalist to right this terrible wrong that has befallen humankind.